DESC: 100% Edible: New Greenies dental chews are 100% edible which means that there isn't anything in it that your dog can't eat and enjoy. Extremely Soluble: New Greenies dental chews are easy to digest and highly soluble (that means that they break down easily in the digestion process). We talked to a lot of nutritionists and scientists and discovered that the key to solubility lies in the proteins used to make the product. We use 4 very high-quality, easily digested proteins as the building blocks of the new chewy recipe: Gelatin Wheat protein isolate Soy protein isolate Sodium caseinate Greenies Large Size are great for Dogs that are 50-100 lbs/22-45 kg.