DESC: Sibutramine, Generic Meridia is used in the management of obesity, including weight loss and maintenance of weight loss, and should be used in conjunction with a reduced calorie diet.What is sibutramine? Sibutramine affects chemicals in the body that are related to weight maintenance. Sibutramine is used as a short-term supplement to diet and exercise in the treatment of obesity. Sibutramine may also be used for purposes other than those listed in this medication guide